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iCELLigence

Hersteller ACEA Biosciences Inc.

Artikel-Nr.: 2801015

Accessories for xCELLigence Systems

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iCELLigence

Compact in the Incubator, Wi-Fi controlled Assays and Analysis

iCELLigence: The system is controlled via a tablet PC (iPad®) and the work station has capacity for 2x 8-well plates (E-plate L8/E-plate L8 VIEW). It can run assays for testing adhesion, proliferation, cytotoxicity, morphology changes, modulation of barrier function and more. A large cavity volume (up to 650 µL) is available. The tablet PC comes with preinstalled control software and connects to the analyzer via Wi-Fi. 2x 8-well plate capacity covers the needs of labs with small numbers of samples. Capable of working with the co-culture E-plate 16 insert for testing direct cell-cell interactions.

Key Applications

  • Cell QC
  • Adhesion assays
  • Proliferation and Cytotoxicity assays
  • Receptor interaction and Signal pathways
  • Cell-Cell-Interaction assays

Cell-Assays in Real-time, live on the iPad®
Monitors your cell assays in real time using no markers or reporter substances. Small footprint of the work station to be placed into a conventional CO2-incubator. Protocol definition and evaluation of results on-line via iPad®, continuous data transfer from work station to PC via Wi-Fi or batch transfer.

  • Small foot print, versatile: ideal for QA and assay development/optimization
  • Continuous recording of cells response signals in all cell-based assays
  • Optimizes timing for compound application and/or downstream assays
  • Combine it with end-point assays for max data quality
  • Excellent reproducibility and data integrity (<0.3% well failures, <15% intra/inter plate variation)
  • Automatic data acquisition, data stored in station if Wi-Fi connection interrupted
  • Long term experiments under controlled physiological conditions in the incubator
  • Rapid analysis cycles: reading one full E-plate 8 needs less than 10 sec
  • Compact design of analyzer, needs only very small space in incubator
  • Easy to handle, intuitive user interface for programming the test protocol
  • Data Analysis software integrated

Method of Operation
Cells are seeded and grown on an E-plate equipped with gold-plated electrodes. The changes in morphology of the adhered cells cause changes in impedance of the electrodes. This allows to monitor all changes in cell status continuously and dynamically. As data are recorded continuously, this method of real time monitoring produces a wealth of information far superior to classical end-point assays. This technology is currently making its way into drug development, toxicology, cancer research, microbiology and virology.

 

Weiterführende Links zu "iCELLigence"

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Ihr Ansprechpartner
E-Mail: josef.freund@ols-bio.de
T +49 421 276 16 9-0
M +49 160 989 33 113
Systemkomponenten

iCELLigence instrument

iCELLigence Control Unit (Tablet-PC/iPAD®)

iCELLigence Software

Resistor Plate L8 (2x)

Accessory Kit (Tools, Spare Pins)