xCELLigence SP

Hersteller ACEA Biosciences Inc.

Artikel-Nr.: 2801000

Accessories for xCELLigence Systems

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xCELLigence SP

Space saving 96-well Single-Plate System
xCelligence SP:
Single plate system for 96-well E-Plates. Small foot print, minimum space consumption inside the incubator. Run your Real Time Cell Analysis (RTCA) fully automated and label-free to produce data of highest quality and integrity. A broad application range and full kinetic data recorded make this technology far superior to any conventional assays.

Get a wealth of information on the biological status of your cell cultures and even research on direct cell-cell interactions.

Key Applications

  • Classical cell-based assays (proliferation, adhesion, viability, morphology etc.)
  • Cell-toCell interaction assays

Cell-based assays in a 96-well with minimum space consumption
The xCELLigence SP system performs label-free RTCA of cell-based assays in a 96-well format. The compact work station is put into the incubator, experiment control, data acquisition and evaluation is handled by the analyzer and a PC (Laptop) located outside the incubator thus enabling continuous data recording.

  • Standard 96-well format E-Plates
  • Continuous recording of cells response signals in all cell based assays
  • Optimizes timing for compound application and/or downstream assays
  • Optimizes timing for compound application and/or downstream assays)
  • Fully automated data acquisition throughout the whole experiment
  • Combine assays recorded with RTCA with end-point or microscopy assays for maximum information using the E-Plate 96 VIEW
  • Long term experiments under controlled physiological conditions in the incubator
  • Rapid analysis cycles: reading one full E-plate 96 needs only approx. 25 sec
  • Compact design of work station, needs only very small space in incubator
  • Easy to handle, intuitive user interface for programming the test protocol
  • Data Analysis software integrated

Method of Operation
Cells are seeded and grown on an E-plate equipped with gold-plated electrodes. The changes in morphology of the adhered cells cause changes in impedance of the electrodes. This allows to monitor all changes in cell status continuously and dynamically. As data are recorded continuously, this method of real time monitoring produces a wealth of information far superior to classical end-point assays. This technology is currently making its way into drug development, toxicology, cancer research, microbiology and virology.







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RTCA Analyzer

SP work station

Control Unit (Notebook)

RTCA Software

Protector Shield

Frame 96

Resistor Plate 96

Accessory Kit (Tools, Spare Pins)