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Virus infectious titer can be determined using real-time cell analysis (RTCA) + Impedance signal decrease after virus infection of Vero cells was dose-dependent. + RTCA is a reproducible and robust high-throughput virus titration method. + RTCA can be used in viral vaccine process development.

 

Join us for a free Seminar: CELL ASSAYS for Cytotox & Oncology
December 10, 2015 | 13:00 – 14:30 pm | WWU Münster, Institut für Molekulare Zellbiologie, Schlossplatz 5, Erdgeschoss, Kursraum 01

 

Join us for a free Seminar: Cell Assays, refined
October 01, 2015 | 12:00 – 1:30 pm | BFS Gießen, Schubertstraße 81, Room 17.2

 

Newsletter 01/2015 mit Themen rund um Real-Time Cell Assays und das iCELLigence: Dieses gibt es nämlich nur noch diesen Monat mit 33% Preisnachlass!

 

Das iCELLigence ist jetzt kurzzeitig 33% günstiger: Warum Sie nicht zögern sollten jetzt alle Vorteile der Echtzeit-Zell Assays für sich zu nutzen.

 

New open access paper available: Co-culturing human dermal fibroblast enhance the proliferation of colon cancer cells. This is also the 1st study that provides real-time data on fibroblast-mediated migration and invasion kinetics of colon cancer cells.

 

Based on electrical impedance measurements (using the xCELLigence system), the authors established a label-free assay, facilitating the real-time monitoring of T-cell-mediated cytotoxicity. The coculture of peptide-specific T-cell lines with peptide-loaded target cells reproducibly led to a decrease in impedance due to induced apoptosis and detachment of target cells. Comparing our results to the standard CRA assay, we could demonstrate that impedance-based measurements show comparable results after short incubation periods (6 h) but outperform the CRA both in reproducibility and sensitivity after prolonged incubation (24 h), enabling the detection of target cell lysis with an effector to target ratio as low as 0.05:1.