A Visit in the Lab: Migration Assays in Lübeck, Germany

Experimental Oncology: Professor Ungefroren group investigates migrational behavior of carcinoma cells. Lately, several publications attracted a great deal of interest, such as:

Bartscht T, Rosien B, Rades D, Kaufmann R, Biersack H, Lehnert H, Gieseler F, Ungefroren H. Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action. Mol Cancer. 2015;14:199.
DOI: 10.1186/s12943-015-0468-0

or

Carl C, Flindt A, Hartmann J, Dahlke M, Rades D, Dunst J, Lehnert H, Gieseler F, Ungefroren H. Ionizing radiation induces a motile phenotype in human carcinoma cells in vitro through hyperactivation of the TGF-beta signaling pathway. Cell Mol Life Sci. 2016;73:427-43,
DOI: 10.1007/s00018-015-2003-2

Here, Professor Ungefroren explains the contribution of xCELLigence DP technology to the work of his group. 

Find out more: ols-bio.de/cell-migration

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