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xCELLigence RTCA eSight Instrument Bundle

Hersteller ACEA Biosciences Inc.

Artikel-Nr.: 2801926

Zubehör xCELLigence Systeme

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xCELLigence RTCA eSight Instrument Bundle

Simultaneous Live Cell Imaging and xCELLigence Biosensor Analyzes in the Incubator 

xCELLigence eSight: Perform real-time experiments on cell proliferation, cytotoxicity, adhesion, morphology, modulation of barrier function and more. Simultaneously obtain accurate real-time analysis of biosensor signals in combination with visual cell control by Life Cell Imaging.

xCELLigence eSight supports 3 fluorescence channels and a variety of plate formats. A 96-well plate is read by the xCELLigence biosensors in 15 seconds, and 96 wells are processed in 6 minutes. 

Applications

  • Cell Quality Control
  • Cell Adhesion
  • Cell Proliferation
  • Cytotoxicity Assays
  • Receptor Signaling
  • Cell-Cell Interaction

Cell Assays in Real-time
Label-free real-time Monitoring and Imaging of Cellular assays: The dimensions of the analyzer allow easy placement in the incubator. Control and evaluation of the experiment is done online, so that the assay can be monitored continuously.

Analysis Principle

Cultivation of the cells takes place in E-plates. These are equipped with microelectrodes, in a weak electric field the biological status of the cells influences the electrical impedance between the medium and the microelectrode sensors and thus allows to observe disturbances and changes in the cell culture dynamically. Real-time monitoring is therefore far superior to traditional endpoint assay, allowing precise time resolution in the range of seconds, minutes, hours and days.

Simultaneously, imaging procedures are applied in real-time and allow a spatial and temporal continuous view of cell populations. The system thus generates an unprecedented level of detail for any cell-based assay.

  

 

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Weitere Artikel von ACEA Biosciences Inc.
 

Hersteller-Beschreibung "ACEA Biosciences Inc."

ACEA Biosciences’ mission is to provide innovative high performance technologies that advance scientific discovery and improve healthcare.

Founded in 2002, ACEA Biosciences, Inc. is a privately owned biotechnology company that is pioneering the development and commercialization of high performance, cutting edge cell analysis instruments for life science research and clinical diagnostics.

Employing noninvasive impedance microelectrodes in automated high-throughput plate formats, our xCELLigence® Real-Time Cell Analysis (RTCA) instruments maximize the physiological relevance of data extracted from in vitro cellular assays. These instruments enable label-free, real-time monitoring of cell proliferation, cell size/morphology, cell-substrate attachment quality, and cell invasion/migration. By eliminating the time- and labor-intensive steps of traditional methods, RTCA vastly improves efficiency and overall productivity. Moreover, the flexibility, sensitivity, and reproducibility of RTCA make it a standout amongst cell-based assay platforms.

ACEA is also helping to revolutionize the field of flow cytometry by designing and producing high performance, customizable benchtop cytometers at accessible price points. By including features such as 13 fluorescence detection channels with 3 lasers, direct volumetric based cell counting, and a versatile high throughput walkaway autosampler, ACEA’s line of NovoCyte® flow cytometers is raising the bar for what is expected of benchtop machines.

 
Systemkomponenten

xCELLigence RTCA eSight Instrument

xCELLigence RTCA eSight Control Unit (Desktop PC)

xCELLigence RTCA eSight Software, vorinstalliert

Monitor