CASY - Brochures & Applications

 

Brochure / Flyer

CASY Cell Counter and Analyzer - Meet the Legend in Cell-based Research
Label-free cell status monitoring, instantly.

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A New Tool for Your CASY

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CASY - Hefe & Gärung fest im Blick.
Das CASY bietet zuverlässige Qualitätskontrolle für die Brauerei.

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CASY - Yeast & Fermentation under Your Control
Lager or ale? top-cropping or bottom-cropping? Gain control over the whole fermentation process.

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Applications

Toxic Effects of the Antibiotic Ciprofloxacin on Algae Cell Growth
Growth inhibition test with the unicellular green algae R. subcapitata according to OECD guideline 201 using CASY

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Monitoring the Cell Cycle of the Unicellular Green Algae Raphidocelis subcapitata
Analysis of cell growth and proliferation using CASY

The cell cycle of R. subcapitata consists of three phases: growth of the mother cell, cell division
(which includes two divisions of the nucleus), and the release of four autospores. Over a period of 24h, the cell number and size distribution of a synchronized culture was tracked, revealing phases of cell growth and phases of proliferation.

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The Cytotoxicity of Anti-Cancer Drug Combinations
Chemosensitivity assays for novel polychemotherapy regimens using CASY.

A recent study employed CASY to evaluate the cytotoxicity of anti-cancer drug combinations in chemotherapy. Aim was to design novel polychemotherapy regimens with wider therapeutic windows.

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Platelet Counting and Morphology
Implications for Hemocompatibility Testing of Biomaterials

CASY’s capabilities for accurate cell counting, and importantly for straightforward cell volume and aggregate measurement supports standardization of hemocompatibility experiments

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Monitoring Human T Cell Activation in the Context of Immunotherapeutic Approaches

Monitoring Cell Size and Proliferation using CASY
T cell growth and proliferation are two important indicators for T cell function. The CASY system allows a reliable, reproducible and label free determination of both parameters providing first insights whether T cell function is preserved under pathophysiologic conditions.
Moreover, determination of cell size and proliferation are reliable indicators to assess the quality of T cell cultures during expansion for adoptive T cell transfer.

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How Chemicals influence Cell Proliferation, Straightforward Cell Culture Monitoring using CASY TT

Both, reliable cell counting together with CASY’s capabilities for cell viability analysis, enabled us to set up a study monitoring possible cytotoxic and growth-affecting properties of drugs and chemicals to be used in subsequent experiments.
CASY has clearly demonstrated its usability in QC related assays such as proliferation control, viability assays or cell debris monitoring by its reliable, label-free and straightforward measurements and comprehensive data evaluation tools.

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Handling of Cell suspensions with the CyBi®-Drop 3D, Cell Viability Studies

The human leukemia cell line K-562 was used as model system to characterize the influence of the recirculation system and the dispensing pumps of the CyBi®-Drop 3D on the cell viability. Original cell suspensions from cell culture flasks were analyzed in comparison with cell suspensions following multiple recirculation and dispensing with the CyBi®-Drop 3D.
The comparing cell viability studies were performed with the CASY® Cell Counter and Analyzer system (Innovatis), the CellTiter-Blue® Cell Viability Assay (Promega) and microscopic examinations (LSM 510 META, Zeiss). The cell appearance and metabolic activity remained stable over the whole examination period of 10 recirculation cycles.

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Standardisierung der Vitalitätsbestimmung

Die Vitalitätsbestimmung ist beim Arbeiten mit Säugerzellen in der biologischen Forschung, in der Toxikologie und in der biotechnologischen Produktion eine der wichtigsten Methoden zur Qualitätskontrolle von Zellkulturen. BIOspektrum, 04.06

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Using the CASY Cell Counter and Analyzer for Proliferation and Viability Measurement
in Oncological Studies

The CASY Cell Counter and Analyzer is an important improvement in our workflow to investigate the anticancer properties of substance A in lymphoma cells. In addition to using the CASY System for multi-parameter quality control of the cell cultures, including cell concentration, cell viability, cell volume, cell aggregation and cell debris, the system can be used to examine apoptosis induction as early as 24 hours after treatment.

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