Innovating 3D Culture

Stem cells – Spheroids – Organoids – Tissues


  • Reduces cost, time spend and variations
  • Improved viability and maturation
  • Significantly reduced apoptosis & necrosis
  • Homogenous condition for homogeneous results
  • No shear forces and minimized gravity
  • Enabling pathogenic infection studies

Think in new dimensions – CERO is overcoming known limitations of static cultures.

Easy, ready-to-use protocols, standardizable workflows and autoadhesion of cells without any need for Carriers or Matrigel are just a few of the advantages.

As a result, CERO enables high yield expansion of pluripotent stem cells or long term cultivation of tissue for >20 days (Spheroids >80 or Organoids >180).

Cultivating hepatocyte spheroids in CERO considerably improves expansion, differentiation, maturation and hepatic virus infection compared to monolayer culture. Our research takes advantage from healthy cells even from long-term cultures in CERO. Moreover, we are now able to perform 3D long-term culture of human tissue specimen in CERO - a paradigm shift.

Prof. Dr. Heikenwälder, Chronic Inflammation and Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany

Upcoming CERO events ...

09th Apr

CERO Incubator and Bioreactor – Innovating 3D Cell Culture

Webinar | Webinar | 10 am

In this webinar you will get insights into our novel 3D Bioreactor and Incubator „CERO“ suitable for long-term culture of spheroids, organoids and tissues.

Read more ›

15th Apr

Light-Sheet Microscopy Workshop

Workshop | BioSysM & Biocenter, LMU Munich | 9 am

POSTPONED! At the Light Sheet Microscope Workshop, OLS is organizing Hands – on session for CERO – 3D Bioreactor and X-CLARITY – Tissue Clearing Systems. OLS will give short talks and present the technologies to the attendees. Additionally, OLS will provide samples (Spheroids) and Cleared tissues for Light Sheet Microscopy sessions.

Read more ›


Name Article number Description Quote Order
CEROTubes 2800005 CEROTubes (48 units) Quote Order now

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