We have compiled a package supporting Vaccine and Virology research given the current Corona situation.
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus has been identified in December 2019 and the disease has since spread worldwide, leading to an ongoing worldwide pandemic.
The fact that there is no specific, effective treatment or cure for COVID-19 yet, has created a substantial and sustained need for effective research to first to understand the viral microbiology and the pathology of the disease on cells. This means that many questions are arising with regards to drug discovery and development creating further need for cell culture, imaging, diagnostics as well as biobanking.
In our effort to respond to the ongoing siutation, we have compiled a package supporting vaccine, virology and drug discovery research given the current COVID-19 situation. In our experience, we know that vaccine and virology workflows should be simple, robust and cost-effective while allowing allow high-throughput assay development. The whole process should enable continuous sampling with relative ease of setup and little attention requirements. This is undoubtedly in addition to highly reproducible results. CERO, CASY and RTCA xCelligence, a combination which is your fastest way to reliable expansion and infection of cells, quality control and real-time assay development in fields of vaccine production and virology research.
For your drug discovery efforts, constant cell culture monitoring and high throughput imaging is required. For this purpose, we recommend zenCell Owl and Hermes WiScan. Indeed, COVID-19 has created an immediate need for biobanking. This would require high quality cryopreservation products so take a look at our HiSepTM Lymphocyte Separation Media, CryoXLTM – Cryopreservation as well as Cryo Vials. Last but not least, given the effects of COVID-19 on the immune system, there is a growing need of understanding how the immune system responds to the virus, the vaccination and how the cytokine storm occurs. For this purpose, the NovoCyte flow cytometry instruemts, the Namocell single cell dispenser might be of great use!
In Vaccine and Virology, optimization of workflow like expansion of cells, quality control and real-time assay development are of utmost importance.
Vaccine and Virology workflows should be:
CERO, CASY and RTCA xCelliegence, a combination which is your fastest way to reliable expansion and infection of cells, quality control and real-time assay development in fields of vaccine production and virology research.
In following find some information about these devices and descriptions of corona package contents associated with it.
Innovating 3D cell culture
A presentation showing the added value customers will have by using CERO Bioreactor and Incubator in their daily work with suspension cultures conducting viral infections
Establishment and validation of the 3D cultivation system „CERO“ for hepatic spheroids to study viral hepatitis
A poster containing information on Liver Spheroids showing the benefit of CERO in terms of cultivation and infection
Generation of HepaRG Spheroids in the CERO: A 3D model for investigation of Hepatitis B Virus infections
A protocol to generate a 3D model of HepaRG to investigate the dynamics of an HBV infection and also of antiviral therapy along an oxygen gradient
A new way to monitor virus-mediated cytopathogenicity
An AppNote note showing key benefits of the xCELLigence RTCA systems for monitoring virus-mediated cytopathogenicity
Vaccine and Virology Applications
A presentation and a handbook covering the most important applications in the field of vaccine and virology
List of publications on RTCA Technology in vaccine and virology research
All the relevant publications on RTCA technology in vaccine and virology
Virus mediated cytopathogenicity handbook
Handbook containing virus mediated cytopathogenicity
Live Cell Analysis | Dr. Noelle J.A. Ali, Dr. Kathrin Ringwald
In the current times, where several of us are fighting the race against the time to find the cure and prevention for COVID-19, the evaluation and the need for better technologies for virus-mediated cytopathogenicity have become more and more of relevance. The xCELLigence real-time cell analysis (RTCA) from Agilent technologies proves to be one such technology, making use of non-invasive electrical current based measurements.Read more ›
In this video you will learn how whole blood samples are easily processed with the CURIOX Laminar Flow Washer without centrifugation in a biosafety cabinent.