Covid-19 | Corona Package

In Vaccine and Virology, optimization of workflow like expansion of cells, quality control and real-time assay development are of utmost importance.

Vaccine and Virology workflows should be:

simple, robust and cost-effective
allow high-throughput assay development
enable continuous sampling throughout the process
easy to set up and require little attention
provide highly reproducible results

CERO, CASY and RTCA xCelliegence, a combination which is your fastest way to reliable expansion and infection of cells, quality control and real-time assay development in fields of vaccine production and virology research.
In following find some information about these devices and descriptions of corona package contents associated with it.

CERO - 3D benchtop incubator & bioreactor

3D Cell Culture Bioreactor CERO Frontview

CERO is the best choice when it comes to cultivation of spheroids, organoids or even tissue.

improves expansion and cell infection
enables long term maturation and differentiation
minimizes need for manual interaction
reduces demand in consumption of expensive media

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CERO 3D Cell Culture - Downloads

Innovating 3D cell culture

A presentation showing the added value customers will have by using CERO Bioreactor and Incubator in their daily work with suspension cultures conducting viral infections

Establishment and validation of the 3D cultivation system „CERO“ for hepatic spheroids to study viral hepatitis

A poster containing information on Liver Spheroids showing the benefit of CERO in terms of cultivation and infection

Generation of HepaRG Spheroids in the CERO: A 3D model for investigation of Hepatitis B Virus infections

A protocol to generate a 3D model of HepaRG to investigate the dynamics of an HBV infection and also of antiviral therapy along an oxygen gradient

CASY - The legendary Cell Counter that can do so much more

Cell Counter And Analyzer CASY Software Graph

Since decades, CASY proves its reliability and precision in hundreds of places globally every day

new acquisition and analysis software
continuous sampling throughout the process
quality control – detect slightest changes of your cells
results in seconds
- no staining needed
- cell count, cell viability, cell size, cell aggregation and total biomass
hundreds of publications

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CASY Cell Counter - Downloads

Virus infection of Sf9 insect cells infected with Baculo-Virus

CASY App Note presenting a method how to calculate the virus titer (MOI) by analysing the changes in cell volume of Sf9 cells infected with Baculo-Virus

RTCA xCelligence - Reliable tool for studying virus-mediated cytopathogenicity

For many years, RTCA xCelligence technology has been proving its reliability and precision in vaccine and virology research.

fast and high throughput
real-time: quantitative monitoring of CPE
label free and imaging methods combined
accurate, precise and highly reproducible
easy work flow: requires only the addition of virus to host cells

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RTCA xCelligence - Downloads

A new way to monitor virus-mediated cytopathogenicity

An AppNote note showing key benefits of the xCELLigence RTCA systems for monitoring virus-mediated cytopathogenicity

Vaccine and Virology Applications

A presentation and a handbook covering the most important applications in the field of vaccine and virology

List of publications on RTCA Technology in vaccine and virology research

All the relevant publications on RTCA technology in vaccine and virology

Virus mediated cytopathogenicity handbook

Handbook containing virus mediated cytopathogenicity

RTCA xCELLigence - News

Real-Time Cell Analysis and Monitoring of Virus-Mediated Cytopathic Effects

Live Cell Analysis | Dr. Noelle J.A. Ali, Dr. Kathrin Ringwald

In the current times, where several of us are fighting the race against the time to find the cure and prevention for COVID-19, the evaluation and the need for better technologies for virus-mediated cytopathogenicity have become more and more of relevance. The xCELLigence real-time cell analysis (RTCA) from Agilent technologies proves to be one such technology, making use of non-invasive electrical current based measurements.

Curiox Laminar Wash™ Systems for Flow Cytometry

The outbreak of COVID-19 has resulted in shifting priorities for many researchers. Sample handling of COVID-19 samples is extremely important and may need to be conducted in a biosafety cabinet.
With the CURIOX Laminar Cell Washer we provide a proven technology that enables you to:

Process infectious samples completely within a biosafety cabinet
Washing without centrifugation, eliminating aerosolization of potentially infectious samples
Improve consistency of flow cytometry data using centrifuge-less washing
Increase cell retention compared to centrifugation

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In this video you will learn how whole blood samples are easily processed with the CURIOX Laminar Flow Washer without centrifugation in a biosafety cabinent.